Are there side effects of oxytocin for large breeds?

How do puppy energy needs differ from adult dogs?

Side Effects of Oxytocin Yes, the side effects of oxytocin apply to large breeds (such as Newfoundlands) just as they do to smaller dogs. The primary side effect is that oxytocin decreases blood flow to the unborn puppies. To mitigate this risk, veterinarians purposefully administer very small doses. Another issue is that the uterus becomes refractory (stops responding) to oxytocin after a few doses. If a dog’s uterus becomes refractory and she fails to deliver a puppy, or if she is delivering a large litter, a C-section will be required.

Puppy vs. Adult Energy Needs Growing puppies have higher energy (caloric) requirements than adult dogs. To properly support this growth, a puppy’s diet should have a higher protein level and a moderate fat level.

However, it is critical not to overfeed puppies, especially those of large and giant breeds. Providing a puppy with excess calories causes an unhealthy, rapid rate of growth and an increase in body mass that stresses their developing bones. This over-nutrition makes obese puppies significantly more prone to developing degenerative joint and bone diseases.